Pimento cheese, a popular local snack-food/condiment, often eaten in a sandwich on white bread with mayo.
A supermarket shopping cart.
Indiana University-Purdue University at Indianapolis or IUPUI, the acronym that inspired the not-so-flattering nickname.
You may hear the locals refer to the Clinton Presidential Library this way. It does sort of resemble one.
Philadelphia's area code and a colloquial term for Philadelphia itself, as in the following sentence:
"Allen Iverson was really representin' the 215 in Los Angeles last night when he torched Kobe."
A nickname for St. Louis, originating in the Native American burial mounds that were once common to the city.
Children's street game of bygone days, involving pink Spalding (or "spaldeen") ball and broomstick. Now sadly defunct.
(noun) Common nickname for the Minneapolis Star Tribune, a daily newspaper.