Original nickname for the Syracuse University sports teams. No, it has nothing to do with crackers, but rather Syracuse's prominence in the salt trade. The Saltine Warriors then became the Orangemen, and then the more gender-neutral Orange.
The technical definition is an adjective used to describe something as cheap or inferior. New Yorkers use it as a term encompassing all of the souvenirs sold in Times Square that tourists take home with them to remind them of their trip to New York City. (I mean, what else would you call a melamine ash tray shaped like a yellow taxi?) AKA kitsch. Individual items of schlock or kitsch are known as tchotchkes.
Old cable cars that go up the side of Mt Washington
Cookies that have white frosting and chocolate frosting. In many other places they are called half and half cookies.
Slang for a draft beer or the contraption that dispenses a tap beer. You may hear a Milwaukee resident walk in to a bar and ask if there are "any specials on tappers".